When changing some settings in Internet Explorer recently, I stumbled across the “Use SSL 3.0” and “Use TLS 1.2” settings under the Advanced tab of Internet Options. For a long time, I have been running without SSL 2.0, TLS 1.0, and TLS 1.1 enabled, but I wondered if SSL 3.0 is even necessary anymore (TLS superseded SSL 3.0 in 1999). So I unchecked the “Use SSL 3.0” check box. I did the same in my Firefox settings. I ran that way for at least a couple of weeks without any noticeable issues. Then last week I was onsite at a bank and tried to use the Cisco AnyConnect SSL VPN. It did not connect, so I tried it that night from the hotel. It still did not connect. The Cisco IPSEC VPN client worked perfectly. After a couple of days of the AnyConnect client not working, I was about to send an email to one of our network engineers asking if anything had changed when I remembered the “Use SSL 3.0” setting. After re-enabling SSL 3.0 in both IE and Firefox, the AnyConnect client worked. Aside from the SSL 3.0 setting breaking AnyConnect, the more general GOTCHA is that the AnyConnect client uses at least some of the web browser settings when establishing its connection, so I now know to include them when troubleshooting the VPN.