A while back, before the recent VMware ESX upgrade, I was having problems logging into the VC server. As soon as the main console window would pop up, I’d receive “Exception has been thrown by the target of an invocation”. The fix, which I found in the VMWare forums, is to open regedit, go to HKEY_CURRENT_USER/Software/VMWare and delete both entries (Virtual Infrastructure Client and VMWare Infrastructure Client). Doing this, and making sure the compatibility setting was set to Windows XP, let me in successfully.  [more]

http://communities.vmware.com/thread/119422